The micronutrient ?-lipoic acid andits reduced form are potent antioxidants with beneficial effects on endothelial dysfunction.They also regulate gene transcription associated with antioxidant and anti-inflammatorypathways.
[ 20] found that whilst HIF1? was induced at 2 % oxygen with simi-lar kinetics to lower oxygen concentrations, p53 was only stabilised under 0.02 %hypoxia. (2005) Headache in giant cell arteritis andother arteritides.
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