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As described in the Non-cell-to-cell contact Treg effector mechanisms section activation of the adenosine receptor onresponding T cells induces the generation of cAMP and activation of the protein kinase A(PKA) pathway, which results responding/effector T cell anergy. Lumbar spine: Flexion isdecreased at 60 degrees; lateral bending is decreased at25 degrees and guarded bilaterally; hyperextension isnormal at 30 degrees; rotation decreased at 20 degreesbilaterally and elicits discomfort. The heart outcomes prevention evaluationstudy investigators. However, thisclinical trial was the first of its kind to demonstrate that indeed T cells may enter the brain toeffectively kill tumor cells
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